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Cannabinoids 101: Your Complete Guide to Your Favorite Minor Cannabinoids

Written by: Nice Leaf

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Published on

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Time to read 12 min

If you have ever shopped hemp-derived products online, you have probably seen a whole alphabet soup of cannabinoids: Delta-8 THC, THCa, THCp, or HHC. The names can feel technical, but the idea is simple: cannabinoids are natural compounds that interact with your body's endocannabinoid system, which helps regulate things like mood, stress response, appetite and sleep.


In this cannabinoids 101 guide, we are breaking down the hemp-derived cannabinoids you will find at Nice Leaf, what they are, how each tends to feel, and the big picture on legality. We will also share some common-sense tips for shopping online, so you can feel confident you are getting a clean, accurately labeled product from a brand that takes compliance seriously.

Cannabinoids 101: Hemp-Derived vs. Cannabis-Derived (and why it matters)

"Hemp-derived" generally means the cannabinoids are sourced from federally legal hemp (as defined by U.S. law), then extracted and refined into products like gummies and vapes. Many cannabinoids occur naturally in hemp in very small amounts, so products often rely on extraction and conversion processes to reach consistent, useful level.

A Quick Note on the 2018 Farm Bill and Legality

The 2018 Farm Bill federally legalized hemp as Cannabis sativa L. and its derivatives, as long as the hemp meets the legal definition of hemp (commonly discussed as 0.3% delta-9 THC by dry weight at the federal level). In practice, legality gets complicated fast because:

  • Some cannabinoids are not named directly in the Farm Bill.
  • States can (and do) restrict or ban certain hemp-derived cannabinoids regardless of federal positioning.
  • Some states use "total THC" standards or focus on intoxicating effects rather than a single molecule name.

So in this cannabinoids 101 article, we will keep it practical: think "federal framework plus state-by-state reality."

Start Smart: Responsible Use Basics

Before we get into each compound, here are a few best practices that apply to most hemp-derived cannabinoids:

  • Start low and go slow. Especially if you are new or trying a new cannabinoid.
  • Be patient with edibles. Effects can take longer than expected. Taking more too soon is the number one reason people have a bad time.
  • Avoid mixing with alcohol or other intoxicants.
  • Do not drive or operate machinery after using intoxicating cannabinoids.
  • Store securely away from kids and pets.

Now, let's get into the lineup.

Delta-8 THC

What is Delta-8 THC?

Delta-8 THC (delta-8 tetrahydrocannabinol) is a cannabinoid closely related to Delta-9 THC. It occurs naturally in hemp in very small amounts, so most commercial Ddelta-8 is produced from hemp-derived CB through a conversion process.

How Delta-8 Tends to Feel

In many consumer reports, delta-8 is described as a smoother, more mellow THC experience compared to delta-9. People often describe:

  • A relaxed body feel
  • A lighter, more manageable head change
  • A calmer vibe that can still feel euphoric

That said, delta-8 can still be intoxicating. Dose, delivery method, and tolerance matter a lot.

General Legality

Under the 2018 Farm Bill framework, delta-8 products are commonly marketed as hemp-derived when sourced from compliance hemp. However, many states restrict or band delta-8 specifically. Be sure to check your with your local state about accessibility of Delta-8 products.

Delta-9 THC (Hemp-Derived)

What is Delta-9 THC?

Delta-9 THC is the primary psychoactive cannabinoid most people associate with "THC." In hemp products, "hemp-derived delta-9" typically means delta-9 comes from compliant hemp sources and is formulated to meet applicable federal definitions and testing frameworks.

How Delta-9 Tends to Feel

Delta-9 is often described as more pronounced and classic in its effects than delta-8. Many people report:

  • Stronger euphoria
  • More noticeable head change
  • Enhanced sensory perception (music, food, conversation can feel more vivid)
  • Potential for racing thoughts or anxiety at higher amount, especially for sensitive users

Edible delta-9 can feel especially intense because of how your body processes it.


Delta09 is also part of our Delta-8 Blend. We include a measured amount of Delta-9 to round out the experience, adding a more classic THC "fullness" and a more complete overall effect profile than Delta-8 alone. The goal is a better-balanced ride: smoother approachability from delta-8, with a touch of delta-9 to bring depth and clarity to the experience.

General Legality

Federally, hemp is defined in relation to delta-9 THC concentration on a dry-weight basis, but state rules vary widely and enforcement approaches differ. Some states restrict intoxicating hemp products regardless of technical compliance.

THCa (Tetrahydrocannabinolic Acid)

What is THCa?

THCa is acidic, non-intoxicating precursor to THC found in raw cannabis and hemp flower. On its own (unheated), THCa is not typically considered intoxicating. The key detail: heat converts THCa into delta-9 THC through a process called debarboxylation.

How THCa Tends to Feel

This depends heavily on how it is used:

  • Raw THCa (not heated): THCa in its natural form is generally reported as non-intoxicating, because it has not been converted to delta-9 THC.
  • Heated THCa (smoked, vaped, or eaten): Once heat is applied, THCa converts into delta-9 THC. That is when the experience can shift from "not much happening" to a classic THC-style buzz.

Because THCa can turn into delta-9 THC, you should expect the effects to feel like your usual THC experience just got way stronger. If you are used to a certain level of intensity from disposable vape pens or gummies, adding THCa into the mix can make that same product feel like it hits harder, lasts longer, or both.


And if a product already contains Delta-9 THC plus THCa, the experience may feel like a stronger version of that same delta-9 product, because you are getting delta-9 upfront and potentially more delta-9 created from the THCa as it decarboxylates. That is why THCa-heavy products like our THCa Blend are best approached with a "start low and go slow" mindset, especially if you are newer or sensitive to THC.

General Legality

THCa legality is a moving target. Some jurisdictions treat THCa products as hemp if they meet hemp definitions at the time of testing, while others use "total THC" standards or regulate based on conversion potential and intoxication. Always check your state status via Nice Leaf's legality map.

THCp (Tetrahydrocannabiphorol)

What is THCp?

THCp is a minor cannabinoid that has gained quite the popularity because it may interact strongly with cannabinoid receptors a lot more efficiently than other THC cannabinoids. It is typically present in extremely small natural amounts, so many products rely on advanced extraction and formulation to deliver consistent results.

How THCp Tends to Feel

THCp is often described by experienced users as:

  • More intense than expected
  • Longer-lasting than classic THC experiences
  • A deeper, heavier "THC-like" effect profile.

THCp has earned its reputation for a reason. In the original lab research that put THCp on the map, the minor cannabinoid has an affinity for the CB1 receptor that is more than 33 times higher than delta-9 THC.


What does this mean in real life? Higher receptor binding affinity can translate to a cannabinoid experience that feels more intense than you expected, even at smaller amounts, especially for people with lower tolerance. The effect profile is often described as deeply euphoric and heavy, with a higher likelihood of "this is a lot" if you overshoot your dose.


This potency reputation is also a big reason THCp products often come with a higher price tag. You are paying for a cannabinoid that is typically rarer in nature and more demanding to formulate consistently, and one that many consumers seek our specifically for intensity.


Even with the added cost, THCp is widely viewed as one of the most popular bang-for-your-buck cannabinoids for experienced users who want a stronger ride. But it is not for the faint of heart. Start low, go slow, and make sure you know what you are getting yourself into before treating THCp like "just another THC."

General Legality

THCp is not explicitly named in the 2018 Farm Bill, and state laws vary. Some states restrict “intoxicating hemp-derived cannabinoids” broadly, which can include THCp.

THCv (Tetrahydrocannabivarin)

What is THCv?

THCv is a naturally occurring cannabinoid found in certain hemp strains, often discussed as a more functional, "daytime-leaning" compound in the cannabinoid world. It is structurally similar to THC but has its own personality.

How THCv Tends to Feel

Consumer-reported effects often describe THCv as:

  • Clearer and more alert compared to delta-9
  • More "uplifting" than sedating for many people
  • Less heavy on the body, depending on formulation
  • Potentially appetite-modulating for some users (experiences vary)

THCv is a key part of our THCp Blend because it's naturally "sharper," more functional vibe complements THCp's heavier intensity. Instead of an experience that feels one-note and overpowering, THCv helps round things out, adding a clearer, more complete feel to the overall ride. It's still a strong product, but it's designed to feel more balanced and intentional, not just intense for the sake of being intense.

General Legality

As with other minor cannabinoids, THCv’s legal status depends on how it is sourced, how the product is formulated, and how your state defines restricted compounds.

THCh (Tetrahydrocannabihexol)

What is THCh?

THCh is another minor cannabinoid in the "THC family" that has drawn interest for its potential potency and distinct feel. It is typically found in tiny amounts naturally, so commercial availability is tied to modern cannabinoid manufacturing and formulation.

How THCh Tends to Feel

People often describe THCh as:

  • Strong and noticeably euphoric
  • More "heavy" than Delta-8 for many users
  • A slower, deeper physical wave compared to a "daytime-high" the way THCv delivers.

THCh is also included in both our THCp and Blackout blends as the minor cannabinoid helps complete the experience. THCp can deliver a serious level of intensity, and THCh adds extra depth and fullness to the overall profile, creating a more layered ride rather than a flat, one-dimensional "hit." If you are THC-sensitive, treat this blend with respect and take things low and slow!

General Legality

THCh is not explicitly outlined in the Farm Bill by name, and state restrictions on intoxicating hemp can apply. Always verify your local rules as to whether (or not) you can purchase products with THCh in it.

THCb (Tetrahydrocannabutol)

What is THCb?

THCb is a lesser-known cannabinoid that shows up in the expanding conversation around hemp-derived minor cannabinoids. Like several others on this list, it is generally present in very small quantities in nature and often appears in products through specialized processing and formulation.

How THCb Tends to Feel

THCb is commonly described as:

  • THC-adjacent in feel, but with its own "tone"
  • Potentially relaxing and mood-forward
  • Less predictable across brands due to inconsistent standards in the broader market

THCb is a featured cannabinoid in our Blackout Blend, alongside THCh, HHC, and Delta-8. This cocktail of cannabinoids is designed to deliver an experience that's not just intense, but balanced and genuinely enjoyable. Instead of a one-note "too much" high, the blend is formulated to feel fuller, smoother, and more complete.


Think of its Nice Leaf's take on a classic "full spectrum" THC experience: layered effects, better depth, and a more rounded ride that feels intentional form from the first hit to the finish. 

General Legality

THCb's status varies can fall under state restrictions on intoxicating hemp products.

HHC (Hexahyrocannabinol)

What is HHC?

HHC is a hydrogenated cannabinoid. You can think of it as a THC-related compound with a slightly different chemical structure, which influences how it feels and how stable it is in products. In the hemp marketplace, HHC is typically produced hemp-derived starting materials.

How HHC Tends to Feel

HHC is often described as sitting somewhere between delta-8 and delta-9 in intensity, although experiences vary widely. Common reports include:

  • Noticeable euphoria without feeling overwhelmingly "stoned" for some users
  • A balanced head and body effect
  • A smoother ride than delta-9 for some, but stronger than delta-8 for others

Delivery method matters a lot here, especially with inhalables like our HHC Disposable Vape Pens.

General Legality

HHC is not named in the Farm Bill, and several states restrict it.

Cannabinoids 101: How to Choose the Right Cannabinoid for Your Vibe

If you want a simple way to think about these, here an easy framework to follow:

  • Mellow and approachable: Delta-8 (still intoxicating, often described as gentler)
  • Classic THC experience: Hemp-derived delta-9 (stronger, more traditional feel)
  • Flower and conversion-based: THCa (non-intoxicating raw, THC-like when heated)
  • "Strong" minor cannabinoids: THCp, THCh, THCb (often described as clearer and more uplifting)
  • Balanced alternative: HHC (commonly described as mid-range, depending on product)

Your best match depends on your tolerance, your goals (relaxation vs lift vs intensity), and your preferred format (gummies vs vape vs flower).

Buying Cannabinoids Online: What to Look For (and what to avoid)

The hemp marketplace is crowded, and not every product is made with the same standards. If you want to shop confidently, use this checklist.

1) Always Check Third-Party Lab Tests (COAs)

A reputable brand should provide recent, easy-to-find COA (certificate of analysis) from an independent lab. Look for:

  • REQUIREMENT: Cannabinoid potency (does the label match the lab result?)
  • OPTIONAL: residual solvents, heavy metals, pesticides, microbials

2) Watch for Vague Labeling and Mystery Blends

"Proprietary euphoric blend" with no clear cannabinoid breakdown is a major red flag. Transparency matters because different cannabinoids can feel very different.

3) Know the Difference Between Hemp Compliance and State Compliance

A product can be produced under a federal hemp framework and still be restricted where you live. That is why legality tools matter.

4) Prioritize Brands with Real Customer Support and Clear Policies

Look for:

  • A real support channel (Nice Leaf's customer service team is ALWAYS AVAILABLE)
  • Alt-cannabinoids on Discord and Reddit are also great avenues to learn about real-life experiences with these cannabinoids.
  • Clear shipping and returns policies]
  • Age gating, age verification and responsible marketing
  • Honest education not hype)

5) Avoid Extreme Claims

Be cautious of any brand promising to "cure" anxiety, treat depression, or replace prescriptions. Cannabinoids are not approved to diagnose, treat, cure, or prevent diseases. A trustworthy company focuses on quality, compliance, and accurate labeling.

Why Nice Leaf Checks All These Boxes

We are biased, and we are also serious about what we sell. When you shop Nice Leaf, you are choosing a brand that prioritizes:

  • Transparent product information
  • Third-party lab testing
  • Compliance-minded operations
  • Consistent formulations you can actually rely on
  • Education-first support, so you can choose what fits your preferences

If you are using this cannabinoids 101 guide to decide what to try next, the safest move is to stick with a brand that treats quality control like the main product, not an afterthought.

Cannabinoids 101 FAQ

Are these cannabinoids "natural"?

Many cannabinoids occur naturally in hemp, but often at very low levels. Commercial products may use extraction, refinement, and conversion to create consistent cannabinoids from hemp-derived starting materials. What matters most are clean inputs, safe processing, and third-party testing on both the raw materials and the finished product.

Will these cannabinoids get me high?

Some can be intoxicating (delta-8, delta-9, HHC, THCp, THCh, THCb), and THCa can become intoxicating when heated. THCv can be milder and more functional for many users, but experiences vary.

How long do effects last?

It depends on the format. Inhalables tend to come on faster and fade sooner. Edibles usually take longer to kick in and can last significantly longer. If you are new, patience is your best friend.

Are these legal everywhere?

No. The 2018 Farm Bill set a federal hemp framework that legalizes all cannabinoids as long as the delta-9 concentration does not exceed 0.3% on a dry weight basis. Individual states, however, can (and do) regulate or outright restrict its access.

Final Thoughts

The world of hemp-derived cannabinoids is bigger than most people realize, and the best way to enjoy it is to stay informed and shop smart. If you remember only one thing from this cannabinoids 101 guide, make it this: cannabinoid labels are not just marketing, they are chemistry, and chemistry deserves transparency.


Whether you are looking for a mellow delta-8 vibe, a classic delta-9 experience, the unique lane of THCv, or you are exploring newer minor cannabinoids like THCp, THCh, and THCb, quality and compliance should always come first. Nice Leaf is here to make that easier with clearly labeled products, lab testing, and state-aware shopping tools.


If you are ready to explore, shop Nice Leaf's hemp-derived cannabinoid lineup and choose the experience that matches your mood, your tolerance, and your day.